Complex fibroblast response to glucocorticoids may underlie variability of clinical efficacy in the vocal folds

Abstract Similar to the hypertrophic scar and keloids, the efficacy of glucorticoids (GC) for vocal fold injury is highly variable. We previously reported dexamethasone enhanced the pro-fibrotic effects of transforming growth factor (TGF)-β as a potential mechanism for inconsistent clinical outcomes...

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Auteurs principaux: Ryosuke Nakamura, Shigeyuki Mukudai, Renjie Bing, Michael J. Garabedian, Ryan C. Branski
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/c74949bf7687426e93e1fbbc5bb29eb1
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