Three-dimensional in situ morphometrics of Mycobacterium tuberculosis infection within lesions by optical mesoscopy and novel acid-fast staining
Abstract Tuberculosis (TB) preclinical testing relies on in vivo models including the mouse aerosol challenge model. The only method of determining colony morphometrics of TB infection in a tissue in situ is two-dimensional (2D) histopathology. 2D measurements consider heterogeneity within a single...
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Autores principales: | Robert J. Francis, Gillian Robb, Lee McCann, Bhagwati Khatri, James Keeble, Belinda Dagg, Brad Amos, Francisco J. Salguero, Mei Mei Ho, Anwen Bullen, Gail McConnell, Kirsty MacLellan-Gibson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/c753bc9f75174c4195e6c28918b47a23 |
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