Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degeneration.

<h4>Background</h4>Many developmental genes are still active in specific tissues after development is completed. This is the case for the homeobox gene Otx2, an essential actor of forebrain and head development. In adult mouse, Otx2 is strongly expressed in the retina. Mutations of this...

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Autores principales: Francis Béby, Michael Housset, Nicolas Fossat, Coralie Le Greneur, Frédéric Flamant, Pierre Godement, Thomas Lamonerie
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/c7ca3b07f86740ce812c39905222f9e3
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