Generation of Myostatin Gene-Edited Channel Catfish (Ictalurus punctatus) via Zygote Injection of CRISPR/Cas9 System

Generation of Myostatin Gene-Edited Channel Catfish (Ictalurus punctatus) via Zygote Injection of CRISPR/Cas9 System

Abstract The myostatin (MSTN) gene is important because of its role in regulation of skeletal muscle growth in all vertebrates. In this study, CRISPR/Cas9 was utilized to successfully target the channel catfish, Ictalurus punctatus, muscle suppressor gene MSTN. CRISPR/Cas9 induced high rates (88–100...

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Main Authors: Karim Khalil, Medhat Elayat, Elsayed Khalifa, Samer Daghash, Ahmed Elaswad, Michael Miller, Hisham Abdelrahman, Zhi Ye, Ramjie Odin, David Drescher, Khoi Vo, Kamal Gosh, William Bugg, Dalton Robinson, Rex Dunham
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/c7fb0daec0164530b79df13bc376fa68
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https://doaj.org/article/c7fb0daec0164530b79df13bc376fa68

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