Single-Cell RNA-Seq Analysis Reveals the Acquisition of Cancer Stem Cell Traits and Increase of Cell–Cell Signaling during EMT Progression

Intermediate cell states (ICSs) during the epithelial–mesenchymal transition (EMT) are emerging as a driving force of cancer invasion and metastasis. ICSs typically exhibit hybrid epithelial/mesenchymal characteristics as well as cancer stem cell (CSC) traits including proliferation and drug resista...

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Bibliographic Details
Main Authors: Federico Bocci, Peijie Zhou, Qing Nie
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
EMT
Online Access:https://doaj.org/article/c7fc6915883b4b429d859f6f56a7b82b
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