An Important Role for CD4<sup>+</sup> T Cells in Adaptive Immunity to <named-content content-type="genus-species">Toxoplasma gondii</named-content> in Mice Lacking the Transcription Factor Batf3

ABSTRACT Immunity to Toxoplasma gondii at early stages of infection in C57BL/6 mice depends on gamma interferon (IFN-γ) production by NK cells, while at later stages it is primarily mediated by CD8 T cells. We decided to explore the requirement for CD4 T cells during T. gondii infection in Batf3−/−...

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Autores principales: Roxane Tussiwand, Michael S. Behnke, Nicole M. Kretzer, Gary E. Grajales-Reyes, Theresa L. Murphy, Robert D. Schreiber, Kenneth M. Murphy, L. David Sibley
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/c804871fa3f84ebc89bd64eb1e036633
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