HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.

HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.

HIV controllers are rare individuals who spontaneously control HIV replication in the absence of antiretroviral treatment. Emerging evidence indicates that HIV control is mediated through very active cellular immune responses, though how such responses can persist over time without immune exhaustion...

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Detalles Bibliográficos
Autores principales: Benoît Vingert, Santiago Perez-Patrigeon, Patricia Jeannin, Olivier Lambotte, Faroudy Boufassa, Fabrice Lemaître, William W Kwok, Ioannis Theodorou, Jean-François Delfraissy, Jacques Thèze, Lisa A Chakrabarti, ANRS EP36 HIV Controllers Study Group
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/c81fb7067e7e4d438cf0e2cf5a2b20c5
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https://doaj.org/article/c81fb7067e7e4d438cf0e2cf5a2b20c5

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