HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.
HIV controllers are rare individuals who spontaneously control HIV replication in the absence of antiretroviral treatment. Emerging evidence indicates that HIV control is mediated through very active cellular immune responses, though how such responses can persist over time without immune exhaustion...
Saved in:
Main Authors: | Benoît Vingert, Santiago Perez-Patrigeon, Patricia Jeannin, Olivier Lambotte, Faroudy Boufassa, Fabrice Lemaître, William W Kwok, Ioannis Theodorou, Jean-François Delfraissy, Jacques Thèze, Lisa A Chakrabarti, ANRS EP36 HIV Controllers Study Group |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
|
Subjects: | |
Online Access: | https://doaj.org/article/c81fb7067e7e4d438cf0e2cf5a2b20c5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration.
by: Faroudy Boufassa, et al.
Published: (2014) -
The NBC Islands gag
by: Neville Togarewa
Published: (1994) -
Gagging the Samoa Observer
by: Savea Sano Malifa
Published: (2000) -
EDITORIAL: Lies, gags and the future
by: David Robie
Published: (2006) -
NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data
by: Alessandro Montemurro, et al.
Published: (2021)