CALHM1-Mediated ATP Release and Ciliary Beat Frequency Modulation in Nasal Epithelial Cells

Abstract Mechanical stimulation of airway epithelial cells causes apical release of ATP, which increases ciliary beat frequency (CBF) and speeds up mucociliary clearance. The mechanisms responsible for this ATP release are poorly understood. CALHM1, a transmembrane protein with shared structural fea...

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Autores principales: Alan D. Workman, Ryan M. Carey, Bei Chen, Cecil J. Saunders, Philippe Marambaud, Claire H. Mitchell, Michael G. Tordoff, Robert J. Lee, Noam A. Cohen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c82aa564940a442ca73ece8582700867
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