Investigating the targets of MIR-15a and MIR-16-1 in patients with chronic lymphocytic leukemia (CLL).

<h4>Background</h4>MicroRNAs (miRNAs) are short, noncoding RNAs that regulate the expression of multiple target genes. Deregulation of miRNAs is common in human tumorigenesis. The miRNAs, MIR-15a/16-1, at chromosome band 13q14 are down-regulated in the majority of patients with chronic l...

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Détails bibliographiques
Auteurs principaux: Katy Hanlon, Claudius E Rudin, Lorna W Harries
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/c83ca5205432473e816dd3e33701aa01
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