Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex

The GTPase eIF5B is involved in the correct positioning of the initiator Met-tRNAi Me t on the ribosome during the late stages of translation initiation. Here the authors present a cryo-EM structure of the ribosome in complex with eIF5B and Met-tRNAi Met immediately before transition into elongation...

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Autores principales: Jinfan Wang, Jing Wang, Byung-Sik Shin, Joo-Ran Kim, Thomas E. Dever, Joseph D. Puglisi, Israel S. Fernández
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c83cad0e29c9428c8c5db019de2b15ba
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