Phosphorylation of Pit-1 by cyclin-dependent kinase 5 at serine 126 is associated with cell proliferation and poor prognosis in prolactinomas

Pit-1 (POU1F1) is a POU-homeodomain transcription factor, and it is one of the most important tissue-specific transcription factors in pituitary development. Cyclin-dependent kinase 5 (CDK5) is a protein kinase that can phosphorylate many key transcription factors, but the mechanism under which CDK5...

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Bibliographic Details
Main Authors: Xie Weiyan, Fang Qiuyue, Guo Jing, Gong Lei, Li Chuzhong, Zhang Yazhuo
Format: article
Language:EN
Published: De Gruyter 2021
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Online Access:https://doaj.org/article/c899c81e21fd48509122fb156196d24a
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