Phosphorylation of Pit-1 by cyclin-dependent kinase 5 at serine 126 is associated with cell proliferation and poor prognosis in prolactinomas
Pit-1 (POU1F1) is a POU-homeodomain transcription factor, and it is one of the most important tissue-specific transcription factors in pituitary development. Cyclin-dependent kinase 5 (CDK5) is a protein kinase that can phosphorylate many key transcription factors, but the mechanism under which CDK5...
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Autores principales: | Xie Weiyan, Fang Qiuyue, Guo Jing, Gong Lei, Li Chuzhong, Zhang Yazhuo |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
De Gruyter
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c899c81e21fd48509122fb156196d24a |
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