Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization

Abstract Cortical spreading depolarization (CSD) is a propagating wave of tissue depolarization characterized by a large increase of extracellular potassium concentration and prolonged subsequent electrical silencing of neurons. Waves of CSD arise spontaneously in various acute neurological settings...

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Autores principales: Hiromu Monai, Shinnosuke Koketsu, Yoshiaki Shinohara, Takatoshi Ueki, Peter Kusk, Natalie L. Hauglund, Andrew J. Samson, Maiken Nedergaard, Hajime Hirase
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c8a2b7c39e79416a9df5bd64aefd4976
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