De-novo protein function prediction using DNA binding and RNA binding proteins as a test case

Identification of the function of proteins is difficult when there are no structurally or biochemically characterized homologs. Here, the authors present an approach that allows the prediction of nucleic-acid binding proteins based on sequence alone, and they are able to experimentally validate thei...

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Auteurs principaux: Sapir Peled, Olga Leiderman, Rotem Charar, Gilat Efroni, Yaron Shav-Tal, Yanay Ofran
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/c8b8435173fd4ec1ada9d2bf2631624b
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