De-novo protein function prediction using DNA binding and RNA binding proteins as a test case

Identification of the function of proteins is difficult when there are no structurally or biochemically characterized homologs. Here, the authors present an approach that allows the prediction of nucleic-acid binding proteins based on sequence alone, and they are able to experimentally validate thei...

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Autores principales:	Sapir Peled, Olga Leiderman, Rotem Charar, Gilat Efroni, Yaron Shav-Tal, Yanay Ofran
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c8b8435173fd4ec1ada9d2bf2631624b
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spelling	oai:doaj.org-article:c8b8435173fd4ec1ada9d2bf2631624b2021-12-02T17:31:20ZDe-novo protein function prediction using DNA binding and RNA binding proteins as a test case10.1038/ncomms134242041-1723https://doaj.org/article/c8b8435173fd4ec1ada9d2bf2631624b2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13424https://doaj.org/toc/2041-1723Identification of the function of proteins is difficult when there are no structurally or biochemically characterized homologs. Here, the authors present an approach that allows the prediction of nucleic-acid binding proteins based on sequence alone, and they are able to experimentally validate their method.Sapir PeledOlga LeidermanRotem ChararGilat EfroniYaron Shav-TalYanay OfranNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sapir Peled Olga Leiderman Rotem Charar Gilat Efroni Yaron Shav-Tal Yanay Ofran De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
description	Identification of the function of proteins is difficult when there are no structurally or biochemically characterized homologs. Here, the authors present an approach that allows the prediction of nucleic-acid binding proteins based on sequence alone, and they are able to experimentally validate their method.
format	article
author	Sapir Peled Olga Leiderman Rotem Charar Gilat Efroni Yaron Shav-Tal Yanay Ofran
author_facet	Sapir Peled Olga Leiderman Rotem Charar Gilat Efroni Yaron Shav-Tal Yanay Ofran
author_sort	Sapir Peled
title	De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
title_short	De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
title_full	De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
title_fullStr	De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
title_full_unstemmed	De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
title_sort	de-novo protein function prediction using dna binding and rna binding proteins as a test case
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/c8b8435173fd4ec1ada9d2bf2631624b
work_keys_str_mv	AT sapirpeled denovoproteinfunctionpredictionusingdnabindingandrnabindingproteinsasatestcase AT olgaleiderman denovoproteinfunctionpredictionusingdnabindingandrnabindingproteinsasatestcase AT rotemcharar denovoproteinfunctionpredictionusingdnabindingandrnabindingproteinsasatestcase AT gilatefroni denovoproteinfunctionpredictionusingdnabindingandrnabindingproteinsasatestcase AT yaronshavtal denovoproteinfunctionpredictionusingdnabindingandrnabindingproteinsasatestcase AT yanayofran denovoproteinfunctionpredictionusingdnabindingandrnabindingproteinsasatestcase
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De-novo protein function prediction using DNA binding and RNA binding proteins as a test case

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