A computational model of the LGI1 protein suggests a common binding site for ADAM proteins.
Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial epileptic syndrome. The LGI1 gene seems to have a role on the transmission of neuronal messages but the exact molecular me...
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Auteurs principaux: | Emanuela Leonardi, Simonetta Andreazza, Stefano Vanin, Giorgia Busolin, Carlo Nobile, Silvio C E Tosatto |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/c8b9b3cd58cc4a8ba3dd125b1188fd6f |
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