Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts

Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts

While genetic loci shared between cancer types have been identified, cross-cancer relationships for polygenic risk scores have not been well studied. Here, the authors have developed polygenic risk scores for 16 cancers in two large cohorts and identified positive and inverse cross-cancer associatio...

Full description

Saved in:
Bibliographic Details
Main Authors: Rebecca E. Graff, Taylor B. Cavazos, Khanh K. Thai, Linda Kachuri, Sara R. Rashkin, Joshua D. Hoffman, Stacey E. Alexeeff, Maruta Blatchins, Travis J. Meyers, Lancelote Leong, Caroline G. Tai, Nima C. Emami, Douglas A. Corley, Lawrence H. Kushi, Elad Ziv, Stephen K. Van Den Eeden, Eric Jorgenson, Thomas J. Hoffmann, Laurel A. Habel, John S. Witte, Lori C. Sakoda
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Science
Q
Online Access:https://doaj.org/article/c8c7f06feddc43b4892e0628726c8ee8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/c8c7f06feddc43b4892e0628726c8ee8

Similar Items