Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family
Abstract We introduce LytU, a short member of the lysostaphin family of zinc-dependent pentaglycine endopeptidases. It is a potential antimicrobial agent for S. aureus infections and its gene transcription is highly upregulated upon antibiotic treatments along with other genes involved in cell wall...
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Autores principales: | Vytas Raulinaitis, Helena Tossavainen, Olli Aitio, Jarmo T. Juuti, Keiichi Hiramatsu, Vesa Kontinen, Perttu Permi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/c8e8573d85a24ba684ea4c55fbb932a8 |
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