Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family
Abstract We introduce LytU, a short member of the lysostaphin family of zinc-dependent pentaglycine endopeptidases. It is a potential antimicrobial agent for S. aureus infections and its gene transcription is highly upregulated upon antibiotic treatments along with other genes involved in cell wall...
Saved in:
Main Authors: | Vytas Raulinaitis, Helena Tossavainen, Olli Aitio, Jarmo T. Juuti, Keiichi Hiramatsu, Vesa Kontinen, Perttu Permi |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/c8e8573d85a24ba684ea4c55fbb932a8 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Analysis of the peptidoglycan hydrolase complement of Lactobacillus casei and characterization of the major γ-D-glutamyl-L-lysyl-endopeptidase.
by: Krzysztof Regulski, et al.
Published: (2012) -
Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>
by: Peter Mellroth, et al.
Published: (2014) -
Class A Penicillin-Binding Protein-Mediated Cell Wall Synthesis Promotes Structural Integrity during Peptidoglycan Endopeptidase Insufficiency in Vibrio cholerae
by: Shannon G. Murphy, et al.
Published: (2021) -
Synergistic Anti-Staphylococcal Activity Of Niosomal Recombinant Lysostaphin-LL-37
by: Sadeghi S, et al.
Published: (2019) -
Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium
by: Colin C. Kietzman, et al.
Published: (2016)