Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family
Abstract We introduce LytU, a short member of the lysostaphin family of zinc-dependent pentaglycine endopeptidases. It is a potential antimicrobial agent for S. aureus infections and its gene transcription is highly upregulated upon antibiotic treatments along with other genes involved in cell wall...
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Auteurs principaux: | Vytas Raulinaitis, Helena Tossavainen, Olli Aitio, Jarmo T. Juuti, Keiichi Hiramatsu, Vesa Kontinen, Perttu Permi |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Accès en ligne: | https://doaj.org/article/c8e8573d85a24ba684ea4c55fbb932a8 |
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