Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family

Abstract We introduce LytU, a short member of the lysostaphin family of zinc-dependent pentaglycine endopeptidases. It is a potential antimicrobial agent for S. aureus infections and its gene transcription is highly upregulated upon antibiotic treatments along with other genes involved in cell wall...

Full description

Saved in:
Bibliographic Details
Main Authors: Vytas Raulinaitis, Helena Tossavainen, Olli Aitio, Jarmo T. Juuti, Keiichi Hiramatsu, Vesa Kontinen, Perttu Permi
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/c8e8573d85a24ba684ea4c55fbb932a8
Tags: Add Tag
No Tags, Be the first to tag this record!