miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury

miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury

Sepsis and acute lung injury (ALI) are linked to mitochondrial dysfunction; however, the underlying mechanism remains elusive. We previously reported that c-Jun N-terminal protein kinase 2 (JNK2) promotes stress-induced mitophagy by targeting small mitochondrial alternative reading frame (smARF) for...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Jing Yang, Hanh Chi Do-Umehara, Qiao Zhang, Huashan Wang, Changchun Hou, Huali Dong, Edith A. Perez, Marc A. Sala, Kishore R. Anekalla, James M. Walter, Shuwen Liu, Richard G. Wunderink, G.R. Scott Budinger, Jing Liu
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
JNK2
sepsis
lung inflammation and injury
micro RNA (miRNA)
smARF
ubiquitination and degradation
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/c8ed6666624b4fa99b7c46a6cb604a90
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/c8ed6666624b4fa99b7c46a6cb604a90

Ejemplares similares