Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota

Systemic chronic hypoxia is a feature of many diseases and may influence the communication between bone marrow and gut microbiota. Here, the authors show that chronic hypoxia predisposes bone marrow stem cells to premature senescence, which may be due to gut dysbiosis and gut microbiota-derived d-ga...

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Autores principales: Junyue Xing, Yongquan Ying, Chenxi Mao, Yiwei Liu, Tingting Wang, Qian Zhao, Xiaoling Zhang, Fuxia Yan, Hao Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c8fff85f72c84720a26d9d33ef0b27dd
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