Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota
Systemic chronic hypoxia is a feature of many diseases and may influence the communication between bone marrow and gut microbiota. Here, the authors show that chronic hypoxia predisposes bone marrow stem cells to premature senescence, which may be due to gut dysbiosis and gut microbiota-derived d-ga...
Saved in:
Main Authors: | Junyue Xing, Yongquan Ying, Chenxi Mao, Yiwei Liu, Tingting Wang, Qian Zhao, Xiaoling Zhang, Fuxia Yan, Hao Zhang |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
|
Subjects: | |
Online Access: | https://doaj.org/article/c8fff85f72c84720a26d9d33ef0b27dd |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Hydroxyurea Induces Bone Marrow Mesenchymal Stromal Cells Senescence and Modifies Cell Functionality In Vitro
by: Sunčica Kapor, et al.
Published: (2021) -
Curcumin Alleviates the Senescence of Canine Bone Marrow Mesenchymal Stem Cells during In Vitro Expansion by Activating the Autophagy Pathway
by: Jiaqiang Deng, et al.
Published: (2021) -
Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms
by: Hao Li, et al.
Published: (2020) -
The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis
by: James Doonan, et al.
Published: (2019) -
Commensal Gut Microbiota Immunomodulatory Actions in Bone Marrow and Liver have Catabolic Effects on Skeletal Homeostasis in Health
by: Chad M. Novince, et al.
Published: (2017)