Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota

Systemic chronic hypoxia is a feature of many diseases and may influence the communication between bone marrow and gut microbiota. Here, the authors show that chronic hypoxia predisposes bone marrow stem cells to premature senescence, which may be due to gut dysbiosis and gut microbiota-derived d-ga...

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Bibliographic Details
Main Authors: Junyue Xing, Yongquan Ying, Chenxi Mao, Yiwei Liu, Tingting Wang, Qian Zhao, Xiaoling Zhang, Fuxia Yan, Hao Zhang
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/c8fff85f72c84720a26d9d33ef0b27dd
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