Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants' spike protein-an in silico analysis.
Two SARS-CoV-2 variants of concern showing increased transmissibility relative to the Wuhan virus have recently been identified. Although neither variant appears to cause more severe illness nor increased risk of death, the faster spread of the virus is a major threat. Using computational tools, we...
Enregistré dans:
Auteurs principaux: | Suman Pokhrel, Benjamin R Kraemer, Lucia Lee, Kate Samardzic, Daria Mochly-Rosen |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/c9044de64c9c4b3d92b56c6ee24c1299 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Characterization of SARS-CoV-2 Variants N501Y.V1 and N501Y.V2 Spike on Viral Infectivity
par: Haijun Tang, et autres
Publié: (2021) -
Corrigendum: Characterization of SARS-CoV-2 Variants N501Y.V1 and N501Y.V2 Spike on Viral Infectivity
par: Haijun Tang, et autres
Publié: (2021) -
Replicative Fitness of a SARS-CoV-2 20I/501Y.V1 Variant from Lineage B.1.1.7 in Human Reconstituted Bronchial Epithelium
par: Franck Touret, et autres
Publié: (2021) -
Natural variants in SARS-CoV-2 Spike protein pinpoint structural and functional hotspots with implications for prophylaxis and therapeutic strategies
par: Suman Pokhrel, et autres
Publié: (2021) -
N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2
par: Fang Tian, et autres
Publié: (2021)