Direct and Indirect Effect of TGFβ on Treg Transendothelial Recruitment in HCC Tissue Microenvironment
The balance between anti-tumor and tumor-promoting immune cells, such as CD4+ Th1 and regulatory T cells (Tregs), respectively, is assumed to dictate the progression of hepatocellular carcinoma (HCC). The transforming growth factor beta (TGFβ) markedly shapes the HCC microenvironment, regulating the...
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Main Authors: | Francesco Dituri, Serena Mancarella, Grazia Serino, Nada Chaoul, Luigi Giovanni Lupo, Erica Villa, Isabel Fabregat, Gianluigi Giannelli |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Online Access: | https://doaj.org/article/c90e38a8b00d4aaca1ef67cb9ba119a3 |
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