Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship
Introduction: Although the efficacy of hydroxyurea (HU) in inhibiting erythrocyte sickling has been well demonstrated, the action of this drug on human neutrophils and the mechanism by which it improves the manifestations of the disease have not been studied thoroughly. We aimed to investigate the c...
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Autores principales: | , , |
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Formato: | article |
Lenguaje: | EN |
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Elsevier
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/c923064b0797471aa27a538ff3a97fb9 |
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