Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus

Failure of the ependymal cell layer that lines the ventricular surfaces of the brain can result in fetal hydrocephalus. Park et al. reveal a role for the Hippo pathway gene Yap in the generation of ependymal cells, and show that suppression of Yap is observed in a model of hydrocephalus.

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Autores principales: Raehee Park, Uk Yeol Moon, Jun Young Park, Lucinda J. Hughes, Randy L. Johnson, Seo-Hee Cho, Seonhee Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/c946f2033a91434ead953a458b67b434
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