Upregulation of IRF9 Contributes to Pulmonary Artery Smooth Muscle Cell Proliferation During Pulmonary Arterial Hypertension

Abnormal proliferation of pulmonary artery smooth muscle cells (PASMCs) is a critical pathological feature in the pathogenesis of pulmonary arterial hypertension (PAH), but the regulatory mechanisms remain largely unknown. Herein, we demonstrated that interferon regulatory factor 9 (IRF9) accelerate...

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Bibliographic Details
Main Authors: Yong-Jie Chen, Yi Li, Xian Guo, Bo Huo, Yue Chen, Yi He, Rui Xiao, Xue-Hai Zhu, Ding-Sheng Jiang, Xiang Wei
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
Akt
Online Access:https://doaj.org/article/c9564169d54848e2847d1cacb309cfc6
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