Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration

Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration

Schistosomiasis control strategies rely on mass drug administration (MDA) using praziquantel. Here, Berger et al. perform whole-genome sequencing of larvae from infected children across Ugandan regions with differing MDA histories. They find extensive gene flow with limited positive selection sugges...

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Bibliographic Details
Main Authors: Duncan J. Berger, Thomas Crellen, Poppy H. L. Lamberton, Fiona Allan, Alan Tracey, Jennifer D. Noonan, Narcis B. Kabatereine, Edridah M. Tukahebwa, Moses Adriko, Nancy Holroyd, Joanne P. Webster, Matthew Berriman, James A. Cotton
Format: article
Language:EN
Published: Nature Portfolio 2021
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Science
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Online Access:https://doaj.org/article/c962db34a2b7473d882bdf56bb9ca5af
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https://doaj.org/article/c962db34a2b7473d882bdf56bb9ca5af

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