Escin induces apoptosis in ovarian cancer cell line by triggering S-phase cell cycle arrest and p38 MAPK/ERK pathway inhibition

Background: Ovarian cancer (OC), is a common malignant tumors in the female reproductive system with the increased mortality rate. The occurrence of OC is elevating rapidly in recent decades. Escin is a triterpene saponin reported to possess the significant biological activities. Objective: The curr...

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Autores principales: Wei Zhao, Yongxia Lao, Yang Liu, Jiqin Niu, Zhihui Xiao, Palanisamy Arulselvan, Jian Shen
Formato: article
Lenguaje:EN
Publicado: Elsevier 2022
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Acceso en línea:https://doaj.org/article/c968d8f1e8fb4175afa1f937af430be2
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