TRAIL sensitivity of nasopharyngeal cancer cells involves redox dependent upregulation of TMTC2 and its interaction with membrane caspase-3

Aims: Preferential expression of receptors for TNF-family related apoptosis inducing ligand (TRAIL), DR4 and DR5 makes TRAIL an attractive anti-cancer therapeutic. However, the efficacy of targeting death receptors has not been extensively studied in nasopharyngeal cancer (NPC). Here we investigated...

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Autores principales: Deepika Raman, Patricia Tay, Jayshree L. Hirpara, Dan Liu, Shazib Pervaiz
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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NPC
Acceso en línea:https://doaj.org/article/c988189fef44465cb005a770bf3e81f5
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