Intrinsic limits to gene regulation by global crosstalk

Limited specificity of transcription factor-DNA interactions leads to crosstalk in gene regulation. Here the authors consider global crosstalk in regulatory networks of growing size and complexity, and show that it imposes constraints on gene regulation and on the evolution of regulatory networks.

Guardado en:
Detalles Bibliográficos
Autores principales: Tamar Friedlander, Roshan Prizak, Călin C. Guet, Nicholas H. Barton, Gašper Tkačik
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/c992d8eba18c4f6c9db2333ee90aa8f3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!