Characterization of the targeting signal in mitochondrial β-barrel proteins
Mitochondrial β-barrel proteins are synthesized in the cytosol before being targeted to the organelle. Here, Jores et al.show that a specialized hydrophobic β-hairpin motif is the previously undefined targeting sequence and is recognized by the mitochondrial outer membrane translocase.
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Main Authors: | Tobias Jores, Anna Klinger, Lucia E. Groß, Shin Kawano, Nadine Flinner, Elke Duchardt-Ferner, Jens Wöhnert, Hubert Kalbacher, Toshiya Endo, Enrico Schleiff, Doron Rapaport |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Subjects: | |
Online Access: | https://doaj.org/article/c9998c7467d44b55904de822a28f1633 |
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