Finding inhibitors for PCSK9 using computational methods.

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is one of the key targets for atherosclerosis drug development as its binding with low-density lipoprotein receptor leads to atherosclerosis. The protein-ligand interaction helps to understand the actual mechanism for the pharmacological action....

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Autores principales: Rida Zainab, Afshan Kaleem, Michał B Ponczek, Roheena Abdullah, Mehwish Iqtedar, Daniel C Hoessli
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/c99e97c78a2c47ea9969b0b623c9f424
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