Finding inhibitors for PCSK9 using computational methods.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is one of the key targets for atherosclerosis drug development as its binding with low-density lipoprotein receptor leads to atherosclerosis. The protein-ligand interaction helps to understand the actual mechanism for the pharmacological action....
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Auteurs principaux: | Rida Zainab, Afshan Kaleem, Michał B Ponczek, Roheena Abdullah, Mehwish Iqtedar, Daniel C Hoessli |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2021
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Accès en ligne: | https://doaj.org/article/c99e97c78a2c47ea9969b0b623c9f424 |
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