Strong <italic toggle="yes">In Vivo</italic> Inhibition of HIV-1 Replication by Nullbasic, a Tat Mutant
ABSTRACT Nullbasic is a mutant form of the HIV-1 transcriptional activator protein (Tat) that strongly inhibits HIV-1 transcription and replication in lymphocytes in vitro. To investigate Nullbasic inhibition in vivo, we employed an NSG mouse model where animals were engrafted with primary human CD4...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2019
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| Subjects: | |
| Online Access: | https://doaj.org/article/c9a71731e6fa47759ced68c46a9dda02 |
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