Total synthesis of teixobactin

Teixobactin is a recently identified antibiotic that shows activity against drug resistant strains of bacteria. Here, the authors report a highly convergent total synthesis of this natural product, with sufficient flexibility to also allow the synthesis of a number of analogues.

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Bibliographic Details
Main Authors: Kang Jin, Iek Hou Sam, Kathy Hiu Laam Po, Du’an Lin, Ebrahim H. Ghazvini Zadeh, Sheng Chen, Yu Yuan, Xuechen Li
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Q
Online Access:https://doaj.org/article/c9a7a6fa33b54788b18312b4f41ae8cb
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