Total synthesis of teixobactin

Teixobactin is a recently identified antibiotic that shows activity against drug resistant strains of bacteria. Here, the authors report a highly convergent total synthesis of this natural product, with sufficient flexibility to also allow the synthesis of a number of analogues.

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Autores principales:	Kang Jin, Iek Hou Sam, Kathy Hiu Laam Po, Du’an Lin, Ebrahim H. Ghazvini Zadeh, Sheng Chen, Yu Yuan, Xuechen Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c9a7a6fa33b54788b18312b4f41ae8cb
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spelling	oai:doaj.org-article:c9a7a6fa33b54788b18312b4f41ae8cb2021-12-02T16:50:56ZTotal synthesis of teixobactin10.1038/ncomms123942041-1723https://doaj.org/article/c9a7a6fa33b54788b18312b4f41ae8cb2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12394https://doaj.org/toc/2041-1723Teixobactin is a recently identified antibiotic that shows activity against drug resistant strains of bacteria. Here, the authors report a highly convergent total synthesis of this natural product, with sufficient flexibility to also allow the synthesis of a number of analogues.Kang JinIek Hou SamKathy Hiu Laam PoDu’an LinEbrahim H. Ghazvini ZadehSheng ChenYu YuanXuechen LiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-6 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kang Jin Iek Hou Sam Kathy Hiu Laam Po Du’an Lin Ebrahim H. Ghazvini Zadeh Sheng Chen Yu Yuan Xuechen Li Total synthesis of teixobactin
description	Teixobactin is a recently identified antibiotic that shows activity against drug resistant strains of bacteria. Here, the authors report a highly convergent total synthesis of this natural product, with sufficient flexibility to also allow the synthesis of a number of analogues.
format	article
author	Kang Jin Iek Hou Sam Kathy Hiu Laam Po Du’an Lin Ebrahim H. Ghazvini Zadeh Sheng Chen Yu Yuan Xuechen Li
author_facet	Kang Jin Iek Hou Sam Kathy Hiu Laam Po Du’an Lin Ebrahim H. Ghazvini Zadeh Sheng Chen Yu Yuan Xuechen Li
author_sort	Kang Jin
title	Total synthesis of teixobactin
title_short	Total synthesis of teixobactin
title_full	Total synthesis of teixobactin
title_fullStr	Total synthesis of teixobactin
title_full_unstemmed	Total synthesis of teixobactin
title_sort	total synthesis of teixobactin
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/c9a7a6fa33b54788b18312b4f41ae8cb
work_keys_str_mv	AT kangjin totalsynthesisofteixobactin AT iekhousam totalsynthesisofteixobactin AT kathyhiulaampo totalsynthesisofteixobactin AT duanlin totalsynthesisofteixobactin AT ebrahimhghazvinizadeh totalsynthesisofteixobactin AT shengchen totalsynthesisofteixobactin AT yuyuan totalsynthesisofteixobactin AT xuechenli totalsynthesisofteixobactin
_version_	1718383006605901824

Total synthesis of teixobactin

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