Exposure of Salmonella biofilms to antibiotic concentrations rapidly selects resistance with collateral tradeoffs

Abstract Most bacteria in nature exist in biofilms, which are inherently tolerant to antibiotics. There is currently very limited understanding of how biofilms evolve in response to sub-lethal concentrations of antimicrobials. In this study, we use a biofilm evolution model to study the effects of s...

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Bibliographic Details
Main Authors: Eleftheria Trampari, Emma R. Holden, Gregory J. Wickham, Anuradha Ravi, Leonardo de Oliveira Martins, George M. Savva, Mark A. Webber
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/c9ba790d305b43acb0b9c148b1734630
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