Computational prediction of intronic microRNA targets using host gene expression reveals novel regulatory mechanisms.

Approximately half of known human miRNAs are located in the introns of protein coding genes. Some of these intronic miRNAs are only expressed when their host gene is and, as such, their steady state expression levels are highly correlated with those of the host gene's mRNA. Recently host gene e...

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Bibliographic Details
Main Authors: M Hossein Radfar, Willy Wong, Quaid Morris
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/c9ebb7bcfe794bfeb499e8150f24a23b
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