Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early Drosophila development.

Transcription factors that drive complex patterns of gene expression during animal development bind to thousands of genomic regions, with quantitative differences in binding across bound regions mediating their activity. While we now have tools to characterize the DNA affinities of these proteins an...

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Autores principales: Tommy Kaplan, Xiao-Yong Li, Peter J Sabo, Sean Thomas, John A Stamatoyannopoulos, Mark D Biggin, Michael B Eisen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/ca16bcd2071d4059993838318aec3dd5
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