A method to identify trace sulfated IgG N-glycans as biomarkers for rheumatoid arthritis

A method to identify trace sulfated IgG N-glycans as biomarkers for rheumatoid arthritis

Post-translational modifications can affect antibody function in health and disease, but identification of all variants is difficult using existing technologies. Here the authors develop a microfluidic method to identify and quantify low-abundance IgG N-glycans and show some of these IgGs can be use...

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Main Authors: Jing-Rong Wang, Wei-Na Gao, Rudolf Grimm, Shibo Jiang, Yong Liang, Hua Ye, Zhan-Guo Li, Lee-Fong Yau, Hao Huang, Ju Liu, Min Jiang, Qiong Meng, Tian-Tian Tong, Hai-Hui Huang, Stephanie Lee, Xing Zeng, Liang Liu, Zhi-Hong Jiang
Format: article
Language:EN
Published: Nature Portfolio 2017
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Science
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Online Access:https://doaj.org/article/ca2ca638cde14bb8b892f0ac694cda79
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https://doaj.org/article/ca2ca638cde14bb8b892f0ac694cda79

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