Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

Abstract Skin aging is driven by intrinsic and extrinsic factors impacting on skin functionality with progressive age. One factor of this multifaceted process is cellular senescence, as it has recently been identified to contribute to a declining tissue functionality in old age. In the skin, senesce...

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Main Authors: Regina Weinmüllner, Barbara Zbiral, Adnan Becirovic, Elena Maria Stelzer, Fabian Nagelreiter, Markus Schosserer, Ingo Lämmermann, Lisa Liendl, Magdalena Lang, Lucia Terlecki-Zaniewicz, Orestis Andriotis, Michael Mildner, Bahar Golabi, Petra Waidhofer-Söllner, Karl Schedle, Gerhard Emsenhuber, Philipp J. Thurner, Erwin Tschachler, Florian Gruber, Johannes Grillari
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Geriatrics
RC952-954.6
Online Access:https://doaj.org/article/ca3243e6958741a2b69658933a36f4cf
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https://doaj.org/article/ca3243e6958741a2b69658933a36f4cf

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