Cautious addition of targeted therapy to PD-1 inhibitors after initial progression of BRAF mutant metastatic melanoma on checkpoint inhibitor therapy

Abstract Background Virtually all metastatic patients with metastatic melanoma who progress after initial treatment with PD-1 or CTLA-4 directed antibodies will die of their disease. Salvage options are urgently needed. It is theoretically attractive to combine immunotherapy with targeted agents in...

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Auteurs principaux: Wolfram Samlowski, Camille Adajar
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/ca3ffe118c9142de8823f3a8fb1082a6
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