Pathogenic <i>BRCA</i> Variants as Biomarkers for Risk in Prostate Cancer

Studies have demonstrated that men with Prostate Cancer (PCa) harboring <i>BRCA2/BRCA1</i> genetic aberrations, are more likely to have worse disease and a poorer prognosis. A mutation in <i>BRCA2</i> is known to confer the highest risk of PCa for men (8.6 fold in men ≤65 yea...

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Autores principales: Ciara S. McNevin, Karen Cadoo, Anne-Marie Baird, Pierre Murchan, Orla Sheils, Ray McDermott, Stephen Finn
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/ca595d192acd4bb1bc768ae9dca5dfe3
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