Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions

Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions

Heterocycles are ubiquitous in bioactive compounds and routes to different substitution patterns are important to access the full substrate space. Here the authors report a route to 4,5,7,8-substituted antiviral fluorescent quinazolines, to allow cellular uptake visualization without external marker...

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Bibliographic Details
Main Authors: Felix E. Held, Anton A. Guryev, Tony Fröhlich, Frank Hampel, Axel Kahnt, Corina Hutterer, Mirjam Steingruber, Hanife Bahsi, Clemens von Bojničić-Kninski, Daniela S. Mattes, Tobias C. Foertsch, Alexander Nesterov-Mueller, Manfred Marschall, Svetlana B. Tsogoeva
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/ca6b3826d1e94ad6b59eb0bddea12063
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https://doaj.org/article/ca6b3826d1e94ad6b59eb0bddea12063

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