Dengue virus-free defective interfering particles have potent and broad anti-dengue virus activity

Li et al. produce a dengue virus (DENV)-derived defective interfering particle (DIP) production cell line that can stably produce infectious virusfree DIPs. The DENV DIPs produced from this system can potently inhibit replication of all DENV serotypes in cells and have the potential to be repurposed...

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Auteurs principaux: Dongsheng Li, Min-Hsuan Lin, Daniel J. Rawle, Hongping Jin, Zhonglan Wu, Lu Wang, Mary Lor, Mazhar Hussain, John Aaskov, David Harrich
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/ca6d677537e941f587164eee3d3acebc
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