Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids

Mammary organoid growth from single primary human cells rely on distinct morphogenetic processes. Here, the authors observe by live cell imaging the importance of the plastic mechanical response of the extracellular matrix and cell migration for the underlying arborized structure formation process.

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Auteurs principaux: B. Buchmann, L. K. Engelbrecht, P. Fernandez, F. P. Hutterer, M. K. Raich, C. H. Scheel, A. R. Bausch
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/ca6fd98434244dba96daeb649f0b2389
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