Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids

Mammary organoid growth from single primary human cells rely on distinct morphogenetic processes. Here, the authors observe by live cell imaging the importance of the plastic mechanical response of the extracellular matrix and cell migration for the underlying arborized structure formation process.

Guardado en:
Detalles Bibliográficos
Autores principales: B. Buchmann, L. K. Engelbrecht, P. Fernandez, F. P. Hutterer, M. K. Raich, C. H. Scheel, A. R. Bausch
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/ca6fd98434244dba96daeb649f0b2389
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Mammary organoid growth from single primary human cells rely on distinct morphogenetic processes. Here, the authors observe by live cell imaging the importance of the plastic mechanical response of the extracellular matrix and cell migration for the underlying arborized structure formation process.